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KMID : 0359319660060010024
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Korean Journal of Veterinary Research
1966 Volume.6 No. 1 p.24 ~ p.30
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Studie son the Effects of Injected Amount of I131 in Uptake and Release Rate by Thyroid in Guinea Pigs
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Abstract
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In order to observe the effect of the injected radioactive iodine-I^(131) on the uptake in thyroid of normal male guinea pigs and P.B.I^(131) conversion ratio of I^(131) in serum, 24 matured male guinea pigs were divided in 4 groups and 35μc, 70μc, 140μc and 280μc per ㎏ of body weight respectively were injected subcutaneously.
1. The uptake rates of radioactveiodine-I^(131) by external counts of thyroidal uptake reached the maximum level of uptake in 24 hours after injection.
2. As the injected amount increases, the uptake rates of maximum levels and release rate were increased.
3. Uptake rate in the removed thyroid have shown no statistical in the 35μc and 70μc groups of injected guinea pigs.
4. There was no statistical significance in 140μc and 280μc groups of injected guinea pigs.
5. P.B.I^(131) conversion ratio of I^(131) in serum was not in proportion to injected amounts: 61.0%(35), 70.2%(70), 75.3%(140) and 64.8%(280).
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